10 Facts About Berberine

Berberine is a plant based substance that’s been used for thousands of years in medicine. Today it is known for several health benefits including helping with insulin sensitivity, longevity and cardiovascular health.

  1. Ancient Traditional Use:
    Berberine has been used in traditional Chinese and Ayurvedic medicine for centuries to treat various ailments, including digestive disorders and infections.
  2. Plant Sources:
    Berberine is naturally found in several plants, including goldenseal, barberry, Oregon grape, and Chinese goldthread.
  3. Bright Yellow Color:
    Berberine has a vibrant yellow color, which is why it has been used as a natural dye for textiles and food coloring.
  4. Multiple Health Benefits:
    Berberine has a wide range of health benefits, including its potential for managing blood sugar levels, improving cholesterol profiles, lowering inflammation, lowering obesity, improving longevity / anti-aging, and supporting cardiovascular health.
  5. AMPK Activation:
    One of the ways berberine exerts its effects is by activating an enzyme called AMP-activated protein kinase (AMPK). AMPK helps regulate energy metabolism and has various health benefits.
  6. Antimicrobial Properties:
    Berberine has potent antimicrobial properties and has been found to inhibit the growth of bacteria, fungi, viruses, and parasites, making it useful in treating infections.
  7. Gut Health Support:
    Berberine can help promote a healthy balance of gut bacteria by increasing the abundance of beneficial bacteria like Akkermansia muciniphila and reducing harmful bacteria.
  8. Potential Anti-Cancer Effects:
    Studies have suggested that berberine may have anti-cancer properties. It has demonstrated the ability to inhibit the growth of cancer cells and promote apoptosis (programmed cell death).
  9. Neuroprotective Effects:
    Berberine has shown potential neuroprotective effects and has been studied for its role in conditions such as Alzheimer’s and Parkinson’s diseases, where it may help protect against neurodegeneration.
  10. Drug Interactions:
    Berberine has the potential to interact with certain medications, particularly those metabolized by the liver enzymes CYP3A4 and CYP2D6. It’s important to consult with a healthcare professional before using berberine alongside any prescription medications.